顾休（吴尊 饰）一身武功高强，是罗界弟子，他在街头被刘齐（胡歌 饰）拦下，刘齐要求他把宝剑交出来，顾休对此不以为然，双方互掐，顾休看到敌人手中的黑棒，心一凝。

看到黑棒，顾休瞳孔快速放大，死亡的恐惧瞬间笼罩在他的心头上，他急忙发出警告：“你敢，我可是那罗界的弟子，杀了我，他们绝对会查到你！”但是刘齐并不为所动，他拿起黑棒要向顾休施放毒招，顾休此时正处于危急之中。

刘齐把毒招施于顾休，顾休只能大量吞下解毒药，此时他的朋友赶到，及时将刘齐击退，但是他们并不知道，刘齐已经将顾休的朋友给毒死。

顾休带着仇恨加入了追杀，他发现刘齐得势，受到了高层的庇护，他便决定暗中追杀，但是他没有想到，他的行踪已经被敌人追究，而他也陷入了绝境。

顾休的朋友为了报仇，加入了追杀，他们冒着生命危险，追踪刘齐，而刘齐也设置了重重阻拦，使得顾休和他的朋友处于险境。

顾休最终以智取刘齐，但是他发现刘齐竟然是一个双面阴谋集团的核心人物，他们的阴谋更深，而且还拥有更大的权力。顾休想要阻止他们，但是时间不够，一场恶性游戏即将开始，而顾休和他的朋友正处在其中……

最终，顾休和他的朋友以智取胜，平定了乱世，但是他们发现，阴谋集团的险恶行为还在继续，顾休和他的朋友又将陷入更加危险的境地，他们将如何抵挡接下来的挑战？本集《连环追杀》就此收尾，悬念留待下一集！

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